جامعة الملك عبدالعزيز كلية الطب برابغ

Pharmacology Department

Cardiovascular Simulation Lab

Computer-assisted learning

Dog blood-pressure and heart-rate trace

Baseline stable
Heart rate
75bpm
Blood pressure
120/80mmHg
Mean arterial pressure
93mmHg
O₂ saturation
98%
CAL recording window
● Mean BP● Heart rate
Heart ratebeats/min
200150100500
Mean BPmmHg
200150100500
BaselineInjectionReturn toward baseline

Trace convention from the demonstrations: black = mean blood pressure; red = heart rate.

Haemodynamic response

Cardiac output and vascular resistance

CO is a qualitative inference; the recordings measure HR and pressure, not stroke volume.
CO
Baseline100% relative
SVR
Baseline100% relative

Interpretation

Awaiting an experiment

Prediction score: —
Rx

Choose a drug, predict the response, and administer it to reveal the mechanism.

Quick guide

Run a complete experiment

  1. 1
    Select the intervention

    Choose a drug, dose, administration pattern, and optional antagonist pretreatment.

  2. 2
    Commit to a prediction

    Predict the direction of HR, mean BP, and SVR before seeing the response.

  3. 3
    Observe the trace

    Separate the direct receptor effect from the final response after baroreflex compensation.

  4. 4
    Explain and test

    Review the mechanism, answer the check question, then compare with another condition.

This is a conceptual teaching model. Values are simulated and must not be used for patient care or clinical dosing.

Knowledge assessment

Cardiovascular pharmacology quiz

Answer all 10 questions. Your score will be added to the experiment report.